完整的透化肌细胞测试系统
温控8孔浴板(尺寸从400μL到1900μL)
大电池安装区域和电动XYZ微定位平台,带电脑控制
控制和测量力,长度和肌节间距(可选900B / 901C)
可与Aurora Scientific 900B / 901C Sarcomere长度软件(VSL / HVSL)集成
简单安装到倒置显微镜
测量力-pCA,kTR,刚度,长度 - 张力和力 - 速度关系
包括用于测量细胞深度的可选光学棱镜
参考文献:
K?tter, Sebastian et al. “Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins.” The Journal of Cell Biology 204.2 (2014): 187-202.
Alegre-Cebollada, Jorge et al. “S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.” Cell 156.6 (2014): 1235-1246.
Hamdani, Nazha et al. “Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.” Cardiovascular Research 97.3 (2013): 464-471.
Chung, Eunhee and Gary M. Diffee. “Effect of aging on power output properties in rat skinned cardiac myocytes.” The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 66.12 (2011): 1267-1273.
Horiguchi, Hiroshi et al. “Fabrication and evaluation of reconstructed cardiac tissue and its application to bio-actuated microdevices.” IEEE Transactions on NanoBioscience 8.4 (2009): 349-355.