Scarab Genomics
Scarab Genomics公司是由威斯康星大学遗传学家弗雷德•布拉特纳(Fred Blattner)组建的一家私营公司,其主要把科研上常用的细菌大肠杆菌分解。布拉特纳希望经他删减过的“纯净基因组”细菌能在实验室和工业中显示出它的安全和高效。并将其市场化
Scarab Genomics was established in 2002. The Clean Genome® E. coli is the result of Dr. Fred Blattner's research at the University of Wisconsin, Madison. Scarab Genomics has licensed the patented reduced genome technology from Wisconsin Alumni Research Foundation on an exclusive, worldwide basis.
Scarab Genomics has bioengineered the Clean Genome® E. coli by deleting over 15% of the genome. Genome reduction optimizes the E. coli as a biological factory. Elimination of recombinogenic or mobile DNA, toxins and virulence genes and non-essential genes provides increased genome and plasmid stability and improved metabolic efficiency. Clean Genome® E. coli is the strain of choice for a wide spectrum of applications ranging from routine cloning to production of biopharmaceuticals.
The Significance of the Scarab
To ancient Egyptians, scarab beetles with their beautiful iridescent carapaces suitable for jewelry were talismans of good luck and represented new life. To Scarab Genomics new life comes when application of synthetic biology leads to improved E. coli strains for research and therapeutic applications.