Nanoprobes
Nanoprobe公司专业生产免疫金标记和免疫测定试验产品。公司建立之初即研发用于检测生物分子的最灵敏的试剂和技术。其独特的金标技术使用化学交联的金属和纳米颗粒团簇作为标记。与胶体金颗粒静电吸附在抗体和蛋白质上的传统免疫金探针不同，本公司的金标是与生物分子在特定位点交联的不带电荷的分子。这使我们的探针具有胶体金不具备的范围和灵活性。

我们的标记可以附着在任何带有反应基的分子上– 蛋白质、多肽、寡核苷酸、小分子和脂类 - 以检测和定位这些分子。其他标记可以与我们的金标共同使用，我们独特的荧光纳米金探针在一个探针中结合了纳米金（Nanogold®）和荧光素，用于荧光和电镜两种技术共同进行样品成像。

新探针可基于天然生物分子的一个片段设计制作，标记可定位于远离结合位点处从而不影响探针与目标位点的结合。

Nanoprobes was founded to develop the most sensitive reagents and technology for detecting biological molecules.

Our unique gold labeling technology uses chemically cross-linked metal clusters and nanoparticles as labels.

Unlike conventional immunogold probes, in which colloidal gold particles are electrostatically adsorbed to antibodies and proteins, our gold labels are uncharged molecules which are cross-linked to specific sites on biomolecules. This gives our probes a range and versatility which is not available with colloidal gold.

Our labels can be attached to any molecule with a reactive group -- proteins, peptides, oligonucleotides, small molecules and lipids -- for detection and localization. Other labels can be combined with our gold labels; our unique FluoroNanogold probes combine Nanogold® and fluorescein into a single probe for imaging a specimen both by fluorescence and electron microscopy.

New probes can be engineered based on any fragment of a naturally occurring biomolecule, and the label can be positioned away from the binding site so it does not interfere with binding.

Our 1.4 nm Nanogold® probes have been cited in over 80 publications, and we are now developing larger cross-linkable labels in order to offer our customers larger covalently linkable probes with the same advantages.