美国LI-COR Biosciences
LI-COR公司一直致力于为全世界的环境、农业和生态研究提供优质的仪器和良好的服务。其科研设备远销100多个国家,通过ISO9001质量体系认证。LI-COR的应用科学家和工程师与各国的大学、政府研究实验室通力合作,为其研究提供高质量的科研设备。
LI-COR Biosciences is a leader in the design and manufacture of instrument systems for biotechnology and environmental research. LI-COR instruments for photosynthesis, carbon dioxide analysis and light measurement are recognized worldwide for standard-setting innovation in plant science research and environmental monitoring. LI-COR is a pioneer in the development of infrared fluorescence labeling and detection systems for such areas as drug discovery and DNA sequencing for genomic research.
Founded in 1971, the privately held company is based in Lincoln, Nebraska, with subsidiaries in Germany and the United Kingdom. LI-COR systems are used in over 100 countries and are supported by a global network of distributors.
LI-COR Biosciences is a leader in the design, manufacture, and marketing of integrated instrument systems for plant biology, biotechnology, drug discovery, and environmental research.
LI-COR instruments for photosynthesis, carbon dioxide analysis, and light measurement are recognized world wide for standard-setting innovation in plant science research and environmental monitoring.
The company pioneered the development of infrared fluorescence labeling and detection systems for DNA sequencing, protein imaging, genotyping, and AFLP® for genomic and proteomic research.
Founded in 1971, the privately held company is based in Lincoln, Nebraska, with subsidiaries near Frankfurt, Germany and in Cambridge, UK. LI-COR systems are used in over 100 countries and are supported by a global network of distributors. LI-COR is ISO 9001:2000 certified.
Company history...
In 1967, a large project to develop sorghum as a world food product was started at the Agronomy Department of the University of Nebraska at Lincoln (UNL). William Biggs was hired as part of the research team and worked on the development of basic research instruments for the project.
A quantum sensor to measure the quantity of light usable to plants for photosynthesis was developed for the project. Scientists from other laboratories around the world began requesting similar instruments, and William Biggs, co-founder, chairman, president and CEO established LI-COR in 1971 to manufacture these sensors and other products.
These instruments provide a broad spectrum of capabilities that range from the measurement of photosynthesis rates by plant physiologists and ecologists, to underwater light measurement by oceanographers and limnologists.
LI-COR introduced the LI-8100 Automated Soil CO2 Flux System in December 2003 . The LI-8100 delivers highly accurate measurements of CO2 flux with minimum alteration of the natural microclimate of the soil. The system features chambers for making both short-term survey and long-term, unattended measurements.
LI-COR introduced the Leaf Chamber Fluorometer in 2001. The Fluorometer is an accessory to company's standard setting LI-6400 Portable Photosynthesis system. The Fluorometer enables the LI-6400 to perform simultaneous measurements of fluorescence and gas exchange over the same leaf area.
LI-COR infrared CO2/H2O analyzers have rapidly become world standards in atmospheric, industrial, and oceanographic research. The innovative LI-7500, an open path CO2/H2O analyzer, was introduced in November of 1999 and the high precision LI-7000 closed path CO2/H2O analyzer was introduced in 2000.
In the early 1980s, LI-COR applied its R & D expertise to the emerging field of biotechnology by starting a collaborative project in automated DNA sequencing with the UNL School of Biological Sciences.
The first instrument, an argon laser-based DNA sequence, was successfully used at the UNL Sequencing Core Lab for many years. Development then began on a small prototype instrument that incorporated a solid-state IR laser and detector because opportunities were seen for significantly improving performance, reliability, and affordability by changing to IR technology. This new ability to attach IR fluorophores with high fluorescence yield to large biomolecules has proven to have broader applications in molecular and cellular biology that LI-COR continues to develop.
After extensive development and testing, the Model 4000 Automated DNA Infrared Sequencer was introduced in 1992. In 1993, this technology was again used in the Model 4000L Long Read IR DNA Sequencing System, which began to set world standards for long read lengths and accuracy.
LI-COR's next development for DNA sequencing and genetic analysis was the IR2 System. IR2 technology utilizes LI-COR IRDye™ fluorescent dyes to expand the productivity and affordability of infrared DNA analysis while furthering superior read lengths, throughput and new applications. In 1999, the system was enhanced with the introduction of e-Sequencing™ and the Global IR2 System that added new software and networking options including Internet connectivity.
Also in 1999, LI-COR announced a business agreement with NEN Life Science Products, Inc., of Boston, MA, making LI-COR NEN’s exclusive contract manufacturer of the NEN Global IR2 DNA sequencing instrument system and exclusive world-wide distributor for the DNA sequencing instruments and DNA sequencing terminator reagents.
The 4300 DNA Analysis System was introduced in 2003. This third generation instrument provided an updating of the IR2 System by incorporating newer technology for the laser and microscope assembly for enhanced sensitivity. An internal server was added to enhance both stand alone and network operation. The 4300 System now includes comprehensive application packages for DNA sequencing, Microsatellite analysis, AFLP® analysis, reverse genetics (Tilling®), and SNP discovery (Ecotilling).
In early 2001, LI-COR released the Odyssey® Infrared Imaging System. The new system offers superior imaging capabilities with wide dynamic range and high sensitivity, enhancing the ability to detect and quantify strong and weak samples on the same blot.
Odyssey delivers superior 2-color Westerns with clear, sharp bands in a fraction of the time and cost of chemiluminescence, and features unprecedented direct detection for a variety of applications, including Western blots, In-Cell Westerns, and protein and DNA gels.
LI-COR applications scientists and engineers are actively involved in the research community, conducting seminars, participating in scientific meetings, and publishing work in leading journals. Close relationships with universities, government research laboratories, and industry guide our product development. LI-COR customers are in the business of research and the company's mission is to provide system solutions of the highest quality to facilitate their research.
LI-COR systems are used in more than 100 countries world-wide. The privately held company employs more than 200 people at its headquarters in Lincoln, Nebraska, field locations in the U.S., and its subsidiaries in Bad Homburg, Germany and Cambridge, UK. LI-COR is an ISO 9001:2000 registered company.
The LI-COR Board of Directors would like to take this opportunity to return thanks to God for His merciful providence in allowing LI-COR to develop and commercialize products, through the collective effort of dedicated employees, that enable the examination of the wonders of His works.