美国GeneGo 
GeneGo是为系统生物学中的数据挖掘应用提供领先的化学信息学和生物信息学软件解决方案的供应商。公司的产品为从基因组学和代谢组学到蛋白质组学和毒理基因组学的研 究与实验提供支持。MetaBase是GeneGo专业研制的哺乳动物生物学与药物化学数据库，是目前在系统生物学领域覆盖范围最广的数据库。 MetaCore是公司的旗舰产品，为系统生物学研究中的通路分析和生物标记物发现提供了完整的数据挖掘工具套件。

MetaDrug是GeneGo的系统药理学平台，在结合化学信息学和生物信息学基础上，该平台为转化医学、免疫学、炎症与肿瘤研究提供了有力的预测工具。GeneGo产 品的客户以知名大学和大型生命科学公司为主，他们遍及欧洲、亚洲和美国。通过与来自业界与学术界的研究者的广泛合作，GeneGo致力于推动生物信息学软件的应用，为加快发现新疗法与生物标记物提供强力支持。

GeneGo的工具和数据库能够帮助研究人员挖掘和定义各种高通量实验数据背后潜在的生物学意义，了解小分子药物在人体组织中的作用。GeneGo公司还为生命科学研究和药物开发的不同应用范围提供了全方位的解决方案，包括从临床前的疾病发现到临床治疗中的NCE应用，其范围涵盖了生物学与化学的所有方面。
 

GeneGo is a leading provider of data mining & analysis solutions in systems biology. Our data mining tools and databases help to capture and define the underlying biology behind different types of high-throughput experimental data and understand the effects of small molecule drug compounds in human tissues. We provide systems biology solutions for a full range of applications in life science research and drug development, from pre-clinical discovery and NCE applications to clinical trials, covering all aspects of biology and chemistry.

GeneGo’s flagship bioinformatics product in systems biology, MetaCore™, assists scientists in three main areas:

Drug target selection and validation;
Identification of biomarkers for specific disease states and
Patient profiling in clinical trials.
Whether the data derives from microarray gene expression studies, SNPs, metabolic profiles or high content screening (HCS) assays, MetaCore’s sophisticated analytical data mining tools enable the identification and prioritization of the most relevant pathways, networks and cellular processes affected by the condition. The MetaCore™ suite works on the proprietary content of MetaBase™, GeneGo’s manually curated database of mammalian biology and medicinal chemistry. MetaBase™ is the most comprehensive knowledge base available today in systems biology. It allows scientists to network virtually all known human signaling and metabolic reactions and to understand how bioactive compounds interact with and affect these networks based on experimental data. Our second product, MetaDrug™, is GeneGo’s fully assembled systems pharmacology platform that can be used to predict human metabolites, toxicity and mode of action of novel small molecule compounds.

GeneGo’s customer list for our systems biology product offerings includes the largest life science companies and leading universities and research institutions in the US, Europe and Asia. We partner with a broad group of investigators in academy and industry with matching data analysis technologies, content databases and data analysis projects.

Tatiana Nikolskaya, Ph.D., previously a molecular biologist at the University of Chicago, founded GeneGo in 2000. Based on her extensive wet lab background, Dr. Nikolskaya defined the immediate utility of GeneGo technology for bench researchers as the key objective. The GeneGo multi-disciplinary team includes experts in molecular and systems biology, metabolism, graph theory, human diseases and medicinal chemistry. The company employs over 90 scientists and software developers at the corporate headquarters in St. Joseph, MI, with offices in San Diego, CA and in Moscow, Russia. GeneGo is a private company owned by the management team. Its sales revenues and technology grants fund ongoing research and product development for bioinformatics applications within systems biology.